Explore Protein Dynamics at the Molecular Level — PhD Position in Basel, Switzerland

The University of Basel is offering an exciting, fully funded PhD position in Protein Structural Biology and Biophysics. This opportunity is perfect for highly motivated graduates eager to understand the role of molecular chaperones in human health and disease. You’ll work at the intersection of two advanced laboratories — the Hiller and Schmid labs — employing NMR spectroscopy and single-molecule FRET to uncover how the Hsp90 chaperone facilitates protein folding.

Why Hsp90?
Hsp90 is a critical molecular chaperone involved in folding nearly 20% of all cellular proteins. Its dysfunction is linked to cancer, neurodegeneration, and metabolic disorders. Yet, its mechanisms are still not fully understood — a gap this project aims to bridge.

Your Role:
You will design and conduct experiments using advanced spectroscopy, purify proteins, analyze data, and collaborate in an interdisciplinary, international team. Regular participation in scientific conferences and publications is expected.

What You Need:
Applicants must hold a Master’s in Biochemistry, Biophysics, Structural Biology, or a closely related field. A strong foundation in protein science and a keen interest in advanced biophysical techniques are essential. Prior experience in NMR, FRET, or data analysis tools (Python/MATLAB) is a plus.

What You’ll Get:
Beyond cutting-edge research, you’ll be immersed in Basel’s vibrant academic community, supported by modern facilities at the Biozentrum and the Department of Chemistry. With its central European location and quality of life, Basel is an ideal environment for professional and personal growth.

How to Apply:
Submit your application via the BIPED application portal. Include a motivation letter, CV, academic transcripts, and contact details for at least two referees.

📩 Contact for queries: [email protected], [email protected]
🗓 Start date: January 2026 (negotiable)